SPECT and Effectively Treating OCD | David Jarvis, Ph.D.

3,361 views · Published 3 September 2013 · 0:49 · Indexed 27 September 2026

Channel: AmenClinics · 2013 · Education

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Overactivity in the anterior cingulate gyrus is a common finding within a brain SPECT image for obsessive-compulsive spectrum disorder. With this information, Dr. Jarvis explains that imaging from Amen Clinics helps him and his patients objectify the problem.

There are a number of SPECT studies that report hyperfrontality (increased right and left anterior prefrontal cortex activity and increased anterior cingulate gyrus activity) and increased basal ganglia activity in obsessive-compulsive disorder (OCD). Of interest, hyperactivity in the anterior cingulate gyrus has also been noticed in oppositional defiant disorder and violence. The anterior cingulate gyrus, which is heavily innervated by serotonergic fibers, has been postulated as being involved with shifting attention and cognitive flexibility, deficient in all of these disorders. Treatment with serotonergic antidepressants such as fluoxetine and clomipramine decreases hyperactivity in these areas.

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