Brain Aging and Neural Systems: Insights From Imaging

3,337 views · Published 10 May 2010 · 1:08:54 · Indexed 23 October 2026

Channel: Hebrew University of Jerusalem · 2010 · Science & Technology

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ICNC Seminar

Speaker: William Jagust
Lawrence Berkeley National Laboratory, CA-USA

ICNC lecture hall (Silverman Bldg., Wing 3, 6th floor - Edmond J. Safra Campus)
May 06, 2010, at 17:00

Abstract:

Roland Forum of Brain Repair 2010

Recent studies using a multimodal approach to brain imaging have enabled the study of biochemistry, anatomy, and brain function in the same individuals. In our laboratory, we have used PET imaging to investigate age-related alterations in the brain's dopamine system as well as deposition of beta-amyloid in cognitively intact older people. Both of these biochemical processes produce changes that can be detected with MRI methods including structural imaging, resting BOLD imaging of large-scale resting state networks, and fMRI studies of brain activity. These structural and functional changes, in turn, are related to cognitive decline in healthy older people. This approach can help to define specific systems that are affected by specific underlying processes that cause age-related cognitive decline.

http://icnc.huji.ac.il/seminars/displayseminar.php?id=260&hk=William%20Jagust&title=Brain%20Aging%20and%20Neural%20Systems:Insights%20From%20Imaging

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