Merkel Cells Encode Touch through Adrenergic Synapses

1,169 views · Published 19 December 2018 · 5:02 · Indexed 25 September 2026

Channel: Cell Press · 2018 · Science & Technology

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For more information, see Hoffman et al., Neuron 100/6, http://www.cell.com/neuron/fulltext/S0896-6273(18)30942-5.

Hoffman et al. reveal the machinery underlying neurotransmission at a gentle-touch receptor. Employing Eccles’ classical criteria for a chemical synapse, they show that epithelial Merkel cells communicate with sensory neurons through β2-adrenergic receptors at excitatory synapses.

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