Archive: Genetic Testing for Breast & Ovarian Cancer via Targeted Sequencing
1,084 views · Published 21 November 2013 · 46:08 · Indexed 8 November 2026
Channel: UW Video · 2013 · Education
"Targeted Capture and Massively Parallel Sequencing for Genetic Testing of Breast and Ovarian Cancer" Tomas Walsh, Research Asst. Professor with UW Medicine, describes the development of a comprehensive genetic test for inherited breast and ovarian cancer. The assay, called BROCA, uses DNA capture and next generation sequencing technology and is highly sensitive for identifying mutations in a panel of 21 tumor suppressor genes, including BRCA1, BRCA2, and other genes known to cause inherited breast or ovarian carcinoma. In the present study, BROCA is applied to analyze the germline DNA from 360 women undergoing surgery for primary ovarian, peritoneal, or fallopian tube carcinoma at the University of Washington. The University of Washington is committed to ensuring digital accessibility in our services, programs, and activities. If you encounter accessibility barriers using videos found on this channel, please contact UW Video at [email protected].
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