Researchers use CRISPR to edit DNA outside of the cell for the first time

366 views · Published 21 April 2018 · 1:07 · Indexed 26 October 2026

Channel: Rajamanickam Antonimuthu · 2018 · Science & Technology

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Scientists  have developed a potentially breakthrough CRISPR gene-editing tool. It could allow researchers to take fragments of DNA extracted from human cells, put them into a test tube, and quickly and precisely engineer multiple changes to the genetic code.

This discovery of  Delaware's Gene Editing Institute could rapidly advance personalized cancer care.

This new "cell-free" CRISPR technology is the first CRISPR tool capable of making multiple edits to DNA samples "in vitro," which means in a test tube or petri dish. The advance could have immediate value as a diagnostic tool, replicating the exact genetic mutations found in the tumors of individual cancer patients. Mutations that cause cancer to spread can differ from patient to patient, and being able to quickly identify the correct mutation affecting an individual patient can allow clinicians to implement a more targeted treatment strategy. 

Image Source: Gene Editing Institute 

News Source:  https://www.eurekalert.org/pub_releases/2018-04/b-ruc041718.php

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