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Metformin & Vit B12 deficiency 2018- It's real. - FORD BREWER MD MPH

4,664 views · Published 13 December 2018 · 7:23 · Indexed 26 September 2026

Channel: Dr. Ford Brewer MD MPH · 2018 · Science & Technology

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Dr. Brewer started as an Emergency Doctor.  After seeing too many preventable heart attacks, he went to Johns Hopkins to learn Preventive Medicine.  While there, he went on the run the post-graduate training program (residency) in Preventive Medicine.  From there, he made a career of practicing and managing preventive medicine and primary care clinics.  His later role in this area was Chief Medical Officer for Premise, which has close to 1,000 primary care/prevention clinics.  He was also the Chief Medical Officer for MDLIVE, the second largest telemedicine company. More recently, he founded PrevMed, a heart attack, and stroke prevention clinic.

At PrevMed, we focus on heart attack, stroke, and cognitive decline.  We serve patients who have already experienced an event as well as those who have not developed a diagnosis or event.  Dr. Brewer provides services via telemedicine or in person if you're in the Lexington, KY area.  We find a lot of undiagnosed Pre-Diabetes or Insulin Resistance.  Treating unrecognized risk factors like Pre-Diabetes allows reduction of risk and prevention of disease.

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ABOUT THIS VIDEO:
http://care.diabetesjournals.org/content/35/2/327.figures-only

This video covers metformin and decreased serum vitamin B12. This was a study nested within NHANES, the National Health And Nutrition Examination study. They did confirm a decrease in serum levels of vitamin B12. 
Other studies have shown that it takes about 4 years to see this impact. Government and other standards committees, such as the US Preventive Services Task Force DON'T have recommendations re: this issue. That's because this appears to be a "biochemical" deficiency. In other words, it's not clear that this is related to anemia, depression, neuropathy or other significant problems. 
Normal supplements did not impact these levels. Higher concentration, specific supplementation, such as B12 injections did impact the deficiencies.

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