Tumor suppressor gene variations linked to elevated risk of childhood leukemia, second cancers

3,193 views · Published 4 January 2018 · 0:51 · Indexed 31 October 2026

Channel: St. Jude Children's Research Hospital · 2018 · Nonprofits & Activism

Watch on YouTube

There’s growing evidence that genetics plays an important role in the risk of children developing acute lymphoblastic leukemia. Scientists, led by St. Jude Children’s Research Hospital, found that newly identified germline variations in a key tumor suppressor gene predispose individuals to develop leukemia as children and leave them with a 1-in-4 chance of developing a second cancer later. Researchers believe this finding may change treatment and follow-up for these high-risk patients.

Read the press release: http://ow.ly/O3dI30hAwqI
Read the paper: http://ow.ly/DwDb30hAwMM 
Jun J. Yang, Ph.D.: https://www.stjude.org/yang_jj

More from this channel