New antibiotics, vaccine updates, and are probiotics useful? Microbial Minutes 9-24-18

1,349 views · Published 24 September 2018 · 47:21 · Indexed 31 October 2026

Channel: ASM - Microbes Make Our World · 2018 · Science & Technology

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📄Microbial Minutes 9.24.18 Notes

Chen Q. et al. Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate. mBio. Sept 18 2018. https://mbio.asm.org/content/9/5/e01683-18 

 • ASM Press Release: https://www.asm.org/index.php/newsroom/item/7486-zika-vaccine-shows-promise-for-treating-deadly-brain-cancer 

 • ASM Microbial Sciences blog: https://www.asm.org/index.php/general-science-blog/item/7488-oncolytic-viral-therapies-offer-one-two-punch-to-fight-glioblastoma

 • Popular Science: https://www.popsci.com/zika-glioblastoma-cancer

 • Newsweek: https://www.newsweek.com/glioblastoma-zika-virus-could-destroy-brain-cancer-killed-john-mccain-1125530 


Zmora N. et al. Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics is Associated with Unique Host and Microbiome Features. Cell. September 6 2018. https://www.cell.com/cell/fulltext/S0092-8674(18)31102-4 

Suez J. et al. Post-Antibiotic Gut Mucosal Microbiome Reconstitution is Impaired by Probiotics and Improved by Autologous FMT. Cell September 6 2018. https://www.cell.com/cell/fulltext/S0092-8674(18)31108-5 


 • MTM with Colleen Kraft: https://www.asm.org/index.php/podcasts/meet-the-microbiologist/item/7064-mtm-74 

 • The Guardian: https://www.theguardian.com/science/2018/sep/06/probiotics-not-as-beneficial-for-gut-health-as-previously-thought?CMP=Share_iOSApp_Other 

 • Today: https://www.today.com/health/probiotics-may-not-alter-microbiome-healthy-ways-t136988 

 • ISAPP reply: https://isappscience.org/clinical-evidence-not-microbiota-outcomes-drive-value-probiotics/

 • FDA suggested guidelines: https://www.fda.gov/downloads/Food/GuidanceRegulation/GuidanceDocumentsRegulatoryInformation/UCM619529.pdf


Ray G. et al. Intra-season Waning of Influenza Vaccine Effectiveness. Clinical Infectious Disease. September 10 2018. https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciy770/5094689 

 • CID Commentary: https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciy773/5094713 

 • CIDRAP: http://www.cidrap.umn.edu/news-perspective/2018/09/study-flu-vaccine-protection-starts-wane-within-weeks 

 • Biological Sex and Influenza with Sabra Klein (MTM interview): https://www.asm.org/index.php/podcasts/meet-the-microbiologist/item/7033-biological-sex-and-influenza-with-sabra-klein-mtm73

 • Influenza vaccine and susceptibility with Stacey Schultz-Cherry (MTM interview): https://www.asm.org/index.php/podcasts/meet-the-microbiologist/item/6966-influenza-vaccine-and-susceptibility-mtm-70 


Young R. et al. Developing New Health Technologies for Neglected Diseases: A Pipeline Portfolio Review and Cost Model. Gates Open Research. August 28 2018. https://gatesopenresearch.org/articles/2-23/v2 

 • NYTimes: https://www.nytimes.com/2018/09/07/health/vaccines-hiv-malaria-tuberculosis.html 


Smith PA et al. Optimized Arylomycins Are a New Class of Gram-Negative Antibiotics. Nature. September 12 2018. https://www.nature.com/articles/s41586-018-0483-6 

 • Science Commentary: http://blogs.sciencemag.org/pipeline/archives/2018/09/14/a-new-antibiotic-yes-please 

 • Chemistry World: https://www.chemistryworld.com/news/genentech-antibiotic-quells-resistance/3009495.article 

 • Youtube video: https://www.youtube.com/watch?v=zNrHQl7JEo4 


Tekin E. Prevalence and Patterns of Higher-Order Drug Interactions in Escherichia coli. Systems Biology and Applications. September 3 2018. https://www.nature.com/articles/s41540-018-0069-9 

 • Science Direct: https://www.sciencedaily.com/releases/2018/09/180903101555.htm 
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