Look Who it Was Random video

The Mayo Clinic website re: Metformin Safety is poorly worded, outdated and causing damage

2,916 views · Published 14 December 2017 · 8:01 · Indexed 5 October 2026

Channel: Dr. Ford Brewer MD MPH · 2017 · Science & Technology

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The Mayo clinic web site warns patients of safety with Metformin, specifically for lactic acidosis. It says, "... too much metformin can cause lactic acidosis. The symptoms of lactic acidosis are severe and quick to appear, and usually ossur when other health problems not related to the medicine are present and are very severe, such as heart attack or kidney failure. 
Yet, the Cochrane studies have shown over 70,000 person-years of experience with metformin AND NO EPISODES OF LACTIC ACIDOSIS. JAMA has shown similar studies with MORE EPISODES OF LACTIC ACIDOSIS IN PATIENTS NOT ON METFORMIN. 
Even the FDA has gotten the message. They modified the box warnings re: lactic acidosis and metformin. The key points were to decrease the warnings, even stating metformin is safe for those with mild to moderate kidney disease.

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