ESHG14 Poster: Development of an Ion Torrent AmpliSeq TP53 Panel
477 views · Published 1 June 2014 · 1:42 · Indexed 28 October 2026
Channel: Thermo Fisher Scientific · 2014 · Science & Technology
Download Rosella's poster: http://www.slideshare.net/Life-Technologies-Corp/development-and-verification-of-an-ion-ampliseq-tp53-panel Download all Thermo Fisher Scientific posters from ESHG14: http://ioncommunity.lifetechnologies.com/community/behindthebench/blog/2014/06/01/eshg14-download-our-posters-here-save-on-travel-expense A large amount of data is available on the functional impact of missense mutations in TP53 tumor suppressor gene. and on mutation patterns in many different cancers. TP53 direct sequencing is a time-consuming method with limitations in detection level. Here we describe the development and verification of a TP53 Next Generation Sequencing method based on Ion AmpliSeq technology. Preliminary data demonstrate that the TP53 Ion AmpliSeq panel and Ion Reporter Software analysis solution meets the requirements of clinical research laboratories.
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