Nanonet Force Microscopy for Measuring Cell Forces

448 views · Published 12 July 2016 · 0:06 · Indexed 6 November 2026

Channel: Cell Press · 2016 · Science & Technology

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Asymmetric perturbation of a single cell attached to a suspended fiber network results in a peeling-type failure in 16 seconds. Transient cell force response including cell-fiber adhesion strength is calculated from the deflection of fibers. Also capable of symmetric perturbation, the platform provides new capabilities to investigate single and multi-cell behaviors. See the article by Sheets et al. in the July 12 issue of Biophysical Journal (http://www.cell.com/biophysj/fulltext/S0006-3495(16)30356-3).

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