DISC1 knockdown leads to behavioral deficits

1,779 views · Published 10 February 2010 · 4:22 · Indexed 1 October 2026

Channel: Cell Press · 2010 · Science & Technology

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Watch and listen as Akira Sawa and colleagues take you on a personally guided tour of their findings that transient knockdown of DISC1, a genetic susceptibility factor for schizophrenia, in the pre- and peri-natal stages leads to abnormalities in postnatal mesocortical dopaminergic maturation and behavioral abnormalities after puberty. Read more in Niwa et al., Neuron 65(4).

http://www.cell.com/neuron/abstract/S0896-6273%2810%2900045-0

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