Helicases Find Their Way

4,288 views · Published 4 November 2009 · 6:09 · Indexed 11 October 2026

Channel: Cell Press · 2009 · Science & Technology

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Hexameric helicases unwind DNA or RNA duplexes using ATP as an energy source.  Watch and listen as James Berger and Nathan Thomsen take you on a brief, personally guided tour of their study demonstrating how the Rho helicase couples sequential ATP hydrolysis to RNA unwinding.  The study also reveals why one class of helicases moves 5' to 3'  and another class moves 3' to 5'.

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