Mechanical Criterion for the Rupture of a Cell Membrane under Compression

728 views · Published 20 December 2016 · 0:36 · Indexed 4 November 2026

Channel: Cell Press · 2016 · Science & Technology

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Gonzalez-Rodriguez, Guillou, et al. characterize the rupture of endothelial cell membrane by tilted microindentation. Each microindenter is made from a glass micropipette (left side of each panel). Molten glass from the bead of a microforge (right side of each panel) is added to the tip of each micropipette. The glass adopts a spherical shape due to surface tension. Movie by J. Husson, played at real time. See the article by Gonzalez-Rodriguez et al. (http://www.cell.com/biophysj/fulltext/S0006-3495(16)30999-7) in the December 20 issue of Biophysical Journal.

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