In Vivo Imaging of Neuron and Glial Cell Activity with a New GCaMP5 Reporter Mouse

2,919 views · Published 3 September 2014 · 4:44 · Indexed 6 November 2026

Channel: Cell Press · 2014 · Science & Technology

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In this video abstract, we present a new Cre-dependent GCaMP5G reporter mouse (PC::G5-tdT) targeted the PolR2a locus.  We demonstrate the utility of this mouse line for imaging calcium activity in neurons, astrocytes and microglia. For more information, see Gee et al., Neuron 83(5), http://www.cell.com/neuron/abstract/S0896-6273(14)00635-7.

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