PhotonSABER Casts Light on Learning Mechanisms
584 views · Published 5 September 2018 · 7:30 · Indexed 28 September 2026
Channel: Cell Press · 2018 · Science & Technology
For more information, see Kakegawa et al., Neuron 99/5, http://www.cell.com/neuron/fulltext/S0896-6273(18)30632-9. Long-term depression (LTD) of synaptic transmission is believed as a cellular substrate for learning and memory, but its role remains unclear in vivo. Using a new tool, PhotonSABER, Kakegawa et al. show that LTD at cerebellar synapses is directly responsible for motor learning in vivo.
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