Cytoplasmic Functions for Rbfox1

1,102 views · Published 6 January 2016 · 8:09 · Indexed 8 November 2026

Channel: Cell Press · 2016 · Science & Technology

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For more details, see the paper by Lee et al., Neuron 89(1), at http://www.cell.com/neuron/fulltext/S0896-6273(15)01031-4.

Combining cell biology with RNA sequencing to undertake cytoplasmic transcriptome profiling, Lee and colleagues find that the RNA binding protein Rbfox1 regulates distinct genes in the nucleus and cytoplasm. The cytoplasmic targets of Rbfox1 are enriched in cortical development and autism genes.

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