Evolving Roles for Inhibitory Interneurons in Seizures

1,440 views · Published 9 January 2017 · 4:38 · Indexed 24 October 2026

Channel: Cell Press · 2017 · Science & Technology

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For more information, see Khoshkhoo et al., Neuron 93(2), http://www.cell.com/neuron/fulltext/S0896-6273(16)30911-4.

Using a combination of optogenetics and calcium imaging, Khoshkhoo et al. show how various classes of interneurons play distinct and evolving roles during seizures. They identify vasoactive intestinal polypeptide (VIP)-expressing interneurons as potential targets for seizure control.

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