Adult Astrocytes Contribute to the Synaptic Maturation of New Neurons in the Hippocampus

1,514 views · Published 2 December 2015 · 5:01 · Indexed 24 October 2026

Channel: Cell Press · 2015 · Science & Technology

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In the adult brain, the hippocampus continuously generates new neurons that participate in learning and memory. By releasing D-serine, mature astrocytes enable the maturation of the new neurons they surround. The adult brain may use this mechanism to control the integration of new neurons in hotspots of greater computational need.

For more details, see the paper by Sultan et al., Neuron 88(5), at http://www.cell.com/neuron/abstract/S0896-6273(15)00931-9.

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