Local Translation Regulates Trigeminal Patterning

505 views · Published 11 April 2012 · 5:34 · Indexed 8 October 2026

Channel: Cell Press · 2012 · Science & Technology

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Retrograde signaling mechanisms contribute to the specification of neuronal identity via regulation of gene transcription in the developing nervous system. Sheng-Jian Ji and Samie R. Jaffrey find that local translation in response to target-derived signals plays a role in regulating specific transcriptional responses during neuron specification in the trigeminal ganglia.

For more information, see Ji and Jaffrey, Neuron 74(1).

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