The Good, the Bad and the Epigenetics

1,167 views · Published 17 November 2016 · 4:10 · Indexed 12 November 2026

Channel: Cell Press · 2016 · Science & Technology

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Hank Stunnenberg and colleagues of Radboud University in the Netherlands profile the epigenetic landscapes of "good" and "bad" macrophages and the comparison reveals the epigenetic basis for their differences and how to train the "bad" cells to become "good." Check out the paper at:  http://www.cell.com/cell/fulltext/S0092-8674(16)31316-2.

Boris Novakovic, Ehsan Habibi, Shuang-Yin Wang, Rob J.W. Arts, Robab Davar, Wout Megchelenbrink, Bowon Kim, Tatyana Kuznetsova, Matthijs Kox, Jelle Zwaag, Filomena Matarese, Simon J. van Heeringen, Eva M. Janssen-Megens, Nilofar Sharifi, Cheng Wang, Farid Keramati, Vivien Schoonenberg, Paul Flicek, Laura Clarke, Peter Pickkers, Simon Heath, Ivo Gut, Mihai G. Netea, Joost H.A. Martens, Colin Logie, and Hendrik G. Stunnenberg (2016). -Glucan Reverses the Epigenetic State  of LPS-Induced Immunological Tolerance. Cell 167, 1354-1368.

See article at http://www.cell.com/cell/fulltext/S0092-8674(16)31316-2.

And read more great research at http://www.cell.com/cell/home.

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