Vision Restoration with a Chemical that Exploits Remodeling of Degenerating Retina

2,035 views · Published 19 February 2014 · 6:04 · Indexed 12 November 2026

Channel: Cell Press · 2014 · Science & Technology

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Richard Kramer and Ivan Tochitsky discuss DENAQ, a new chemical photoswitch that restores electrophysiological and behavioral responses to blind mice whose natural rod and cone photoreceptors have degenerated. DENAQ is nontoxic, sensitive enough to work with ordinary daylight, and surprisingly, devoid of side effects on healthy retinal tissue. For more information, see Tochitsky et al., Neuron 81(4).

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