Cortical Membrane Potentials Track Arousal Changes Governing Perceptual Decision Making

1,370 views · Published 1 July 2015 · 8:11 · Indexed 6 November 2026

Channel: Cell Press · 2015 · Science & Technology

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McGinley et al. discover that cortical membrane potentials tightly track changes in arousal indicated by the pupil diameter. Additionally, arousal strongly influences performance on a detection task, revealing that hyperpolarized, quiescent cortical membrane potentials precede large, reliable sensory-evoked synaptic and action potentials during optimal states for behavior.

Check out the paper at http://www.cell.com/neuron/abstract/S0896-6273(15)00477-8.

Matthew J. McGinley, Stephen V. David, David A. McCormick. (2015). Cortical Membrane Potential Signature of Optimal States for Sensory Signal Detection. Neuron 87(1). 

And read more great research at http://www.cell.com/neuron/home.

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