Circadian Lymphocyte Migration through Lymph Nodes

4,322 views · Published 5 October 2017 · 0:55 · Indexed 12 November 2026

Channel: Cell Press · 2017 · Science & Technology

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Movie showing the circadian migration of lymphocytes through lymph nodes. At night onset, increased homing due to higher amounts of lymphocyte CCR7 leads to enhanced lymphocyte counts in the lymph node. During the day, higher S1pr1 expression induces the egression of lymphocytes into efferent lymph. 

Read more from Druzd et al. (2018) in Immunity: http://www.cell.com/immunity/fulltext/S1074-7613(16)30517-9

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