Collective cell migration in the Zebrafish lateral line

1,131 views · Published 17 September 2018 · 0:07 · Indexed 28 October 2026

Channel: Cell Press · 2018 · Science & Technology

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In this video, Wang et al. show that modulating FGF diffusion (by overexpression of Anosmin1, top, compared to wild-type, bottom) impairs the ability of primordium cells of the zebrafish lateral line to migrate. 

Check out the paper at https://www.cell.com/developmental-cell/fulltext/S1534-5807(18)30600-2 

Wang, J., Yin, Y., Lau, S., Sankaran, J., Rothenberg, E., Wohland, T., Martin Meier-Schellersheim, M., and Holger Knaut, H. (2018). Anosmin1 Shuttles Fgf to Facilitate Its Diffusion, Increase Its Local Concentration, and Induce Sensory Organs. Developmental Cell. 46.

And read more great research at Developmental Cell: https://www.cell.com/developmental-cell/home

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