Modeling Recent Human Evolution in Mice by Expression of a Selected EDAR Variant
2,375 views · Published 14 February 2013 · 7:00 · Indexed 18 October 2026
Channel: Cell Press · 2013 · Science & Technology
Pardis Sabeti and colleagues describe their analysis of human sequence data from the 1000 Genomes Project to reveal hundreds of potential adaptive variants. In a second study, the authors engineered mice to express an allele of the human Ectodysplasin receptor, which originated in China ~30,000 years ago, to model recent human evolution. (c) Copyright 2013, The Broad Institute, Inc.
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