Rigor Mortis in C. elegans Organismal Death / Cell Reports, March 6, 2018 (Vol. 22, Issue 10)

295 views · Published 13 March 2018 · 3:35 · Indexed 25 October 2026

Channel: Cell Press · 2018 · Science & Technology

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Gems et al. show that, during aging, senescent pathologies promote mortality by triggering organismal death. When C. elegans organismal death occurs, coupled waves of necrotic muscle hypercontraction (rigor mortis) and intestinal necrosis travel along the body of the worm, causing somatic destruction. Such waves may be triggered by ATP depletion, leading to calcium release, which propagates these coupled waves of death. 
Check out the paper at: http://www.cell.com/cell-reports/fulltext/S2211-1247(18)30231-6

Evgeniy R. Galimov, Rosina E. Pryor, Sarah E. Poole, Alexandre Benedetto, Zachary Pincus, and David Gems (2018). Coupling of Rigor Mortis and Intestinal Necrosis during C. elegans Organismal Death. Cell Reports 22.

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