Conformational Properties of a Moving CENP-E Kinesin Probed with the Tethered Cargo Motion Assay

316 views · Published 5 June 2018 · 0:10 · Indexed 22 October 2026

Channel: Cell Press · 2018 · Science & Technology

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The bead is carried by a kinesin motor along the coverslip-attached microtubule under a small load applied with a force clamp. Simultaneously, the bead is oscillated perpendicular to the microtubule to apply the sideways force and determine extension length of the walking kinesin. See the article by Gudimchuk et al. (https://www.cell.com/biophysj/fulltext/S0006-3495(18)30463-6) in the June 5 issue of Biophysical Journal.

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