Pathway-Specific Plasticity in a Developing Sensory Circuit

503 views · Published 2 August 2017 · 4:40 · Indexed 21 October 2026

Channel: Cell Press · 2017 · Science & Technology

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For more information, see Kaneko et al., Neuron 95/3, http://www.cell.com/neuron/fulltext/S0896-6273(17)30558-5.

Kaneko et al. show a novel mechanism that enables the nervous system to establish long-lasting functional changes in a sensory pathway-specific manner.  They demonstrate that, by enhancing feedback inhibition, noxious inputs during development specifically reduce the function of the nociceptive circuit.

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