Functional cycle of the clamp-loader AAA+ ATPase

1,493 views · Published 4 February 2014 · 0:14 · Indexed 2 October 2026

Channel: Cell Press · 2014 · Science & Technology

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The asymmetrical clamp-loader pentamer (green, with pink ATP) spirals around a DNA double helix (yellow) and binds the sliding-clamp trimer (brown) around the DNA in an open lock-washer position.

Biophysical Highlights from 54 Years of Macromolecular Crystallography
Authors: Jane S. Richardson, David C. Richardson

http://www.cell.com/biophysj/fulltext/S0006-3495(14)00033-2

Published in Biophysical Journal on February 4, 2014

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