Cholinergic Interneurons Are Paused by Receding Excitation

808 views · Published 6 June 2018 · 6:38 · Indexed 12 November 2026

Channel: Cell Press · 2018 · Science & Technology

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For more information, see Zhang et al., Neuron 98/5, http://www.cell.com/neuron/fulltext/S0896-6273(18)30335-0.

Zhang et al. reveal how synchronized pause responses in striatal cholinergic interneurons are driven, through the response of a delayed rectifier current to withdrawal of excitatory inputs, in conjunction with dopamine acting to potentiate the pause during learning.

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