Extensive Growth of Human Induced Pluripotent Stem Cells in Rats after Spinal Cord Injury

818 views · Published 20 August 2014 · 5:53 · Indexed 4 November 2026

Channel: Cell Press · 2014 · Science & Technology

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Human induced pluripotent stem cells (iPSCs) from a healthy 86-year-old male were differentiated into neural stem cells and grafted into adult rats with spinal cord injury. Grafted iPSCs extended remarkably large numbers of axons over nearly the entire length of rat central nervous system and formed connections with rat neurons. For more information, see Lu et al. in Neuron 83(4), http://cell.com/neuron/abstract/S0896-6273(14)00625-4

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