Should Single Strains Suffice?

1,292 views · Published 9 September 2016 · 4:21 · Indexed 12 November 2026

Channel: Cell Press · 2016 · Science & Technology

Watch on YouTube

For more information, see the paper by Sittig et al., http://www.cell.com/neuron/fulltext/S0896-6273(16)30509-8.

Sittig et al. show that the effect of mutant alleles depends heavily on genetic background. In several instances the same mutation increased a phenotype on one background but decreased it on another.

More from this channel

• 2:55 Chromatin shapes the mitotic spindle

  Cell Press

  3,101 views · 30 July 2009

• 5:14 The architecture of adaptation

  Cell Press

  1,732 views · 10 August 2009

• 4:14 Wnts come in small packages

  Cell Press

  2,573 views · 6 October 2009

• 6:09 Helicases Find Their Way

  Cell Press

  4,304 views · 4 November 2009

• 3:16 Fighting Mosquito-Borne Infections

  Cell Press

  2,585 views · 14 December 2009

• 4:29 Leaving Trash with Moms Keeps Daughters Young

  Cell Press

  2,287 views · 21 January 2010

• 4:07 Feedback Control of Vocal Learning

  Cell Press

  704 views · 27 January 2010

• 4:22 DISC1 knockdown leads to behavioral deficits

  Cell Press

  1,789 views · 10 February 2010