Heritable Remodeling of Yeast Multicellularity by an Environmentally Responsive Prion
791 views · Published 14 March 2013 · 5:12 · Indexed 12 November 2026
Channel: Cell Press · 2013 · Science & Technology
Randall Halfmann and colleagues question how budding yeast can acquire multicellular growth forms in response to their environment. The authors describe their work to show that the Mot3 transcription factor forms self-sustaining protein aggregates (prions), which act as epigenetically inherited determinants of cell fate.
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