Huntingtin during Cortical Neurogenesis

1,706 views · Published 4 January 2017 · 5:03 · Indexed 28 October 2026

Channel: Cell Press · 2017 · Science & Technology

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For more information, see Barnat et al., Neuron 93(1), http://www.cell.com/neuron/fulltext/S0896-6273(16)30903-5.

Barnat et al. show that huntingtin, the protein mutated in Huntington’s disease, is a key intrinsic regulator of the RAB11-NCAD polarity pathway during cortical development with direct implications for adult neuronal layering and morphology.

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