A Tip Cell During Blood Vessel Formation

1,125 views · Published 7 December 2018 · 0:14 · Indexed 29 October 2026

Channel: Cell Press · 2018 · Science & Technology

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A 3D view of the leading endothelial cell (tip cell) in a developing blood vessel (isolectionB4-labelled, green). This particular cell possesses numerous thin projections called 'filopodia'. These filopodia are rich in actin filaments (phalloidin-labelled, red). Filopodia explore extracellular cues and are important for the migration of endothelial cells during the formation of new blood vessels, a process known as angiogenesis. Scale: 49.2X49.2X15 um. 

Franco et al., Developmental Cell 15(3), 448-461.

https://www.cell.com/developmental-cell/fulltext/S1534-5807%2808%2900323-7

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